Role of Oncogenic Viruses in Oral Squamous Cell Carcinoma
Authors: Nadeem Jeddy, Radhika T, Muthumeenakshi RM
Abstract
Oral Squamous cell carcinoma (OSCC) is the most common oral malignancy which consistently ranks as one of the sixth
most common cancer with significant morbidity and mortality. Oncogenic viruses, particularly Human Papilloma Virus (HPV) and
Herpes simplex Virus (HSV) play an important role in the pathogenesis of OSCC. These viruses promote cell transformation and
prompt uncontrollable cell generation, resulting in the formation of malignant tumors. The role of oncogenic viruses HPV, HSV in
OSCC is presented. Download this Article
Pages: 01-05
2nd Article
A Simple Technique To Fabricate Immediate Obturator For Esthetic Rehabilitationsimple
Authors: M. Krishnaveni, R. Madhumitha, R. Kamalakannan, C. Nagappan, N. C. Arun Prasad, S. Vinoth
Kumar
Download this Article
Pages: 06-11
3rd Article
Indirect Sinus Lift
Authors:Dr. Rathika Rai, Dr. Vidhya. T. K
AbstractThe indirect sinus lift is a procedure to lift the augment/regenerate
alveolar bone in atrophied residual maxillary posterior alveolar
crest . The posterior maxilla is always considered as difficult
site for the placement of implant than the mandible due to the
presence of various anatomical land mark such as maxillary
sinus. The anatomical structure of maxillary sinus often makes
every dental implant surgeons a challenge task in placement of
endosteal implants in the chronic atrophic maxilla and difficulty
in osseointegration and further functional and aesthetic
implant supported prosthesis. Various techniques in sinus lifting
procedure enables the additional anchorage and stability in
implants placed support in maxillary segments in with atrophic
ridges and pneumatic sinuses. Lack of sufficient bone height
along maxillary sinus poses significant difficulty for placement
of implants in edentulous maxillary jaw. Minimally invasive
sinus augmentation is an effective solution for this problem. In
1960 Boyne introduced sinus lift through lateral access which
was initially used as a pre-prosthetic procedure for removable
complete dentures purpose. In 1980 Boyne and James used
the bone created by sinus lift procedures to place implants. In
pursuit of less invasive techniques , in 1994 Summer’s explained
a technique which offers access to sinus floor through residual
alveolar crest. Using the elasticity of bone, floor dilatation of
sinus was performed to increase the length of implants .
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Pages:12-20
4th Article
influence Of Rbc Count And Haemoglobin Concentration On Platelet Rich Fibrin Network Amomg Different Age Groups And Gender- A Cross Sectional Study. - (Original Article)
Authors:Sonika S, Nivetha R , Esther Nalini H , Arun Kumar Prasad P,
Renuka Devi R
Abstract
AIM: To determine the influence of RBC count and hemoglobin
concentration on the density of PRF network among individuals
of different age groups and gender.
MATERIALS AND METHODS: 82 individuals were divided
into three groups based on their age, Group 1: 20-30 years,
Group 2: 30-45 years, & Group 3: 45-60 years. 3-4 ml of venous
blood samples were collected, PRF were prepared and it was
subjected to histological analysis to determine the age and gender
related changes in the density of PRF network. Hematological
parameters such as Hb concentration and RBC count were also
evaluated and correlated with the density of PRF network.
RESULTS: Group 1 showed predominantly dense fibrin
network, Group 2 showed mixed pattern including both dense
and loose fibrin network and Group 3 showed predominantly
loose fibrin network. However the difference in fibrin network
among different age groups was not statistically significant (p
value-0.14). Among the gender, males showed dense fibrin
network compared to females which was statistically significant
with p value-0.03. There was no statistically significant
correlation between RBC count and density of fibrin network
with p value-0.11. There was a statistically significant correlation
between Hb level and density of fibrin network with p value-0.05.
CONCLUSION: The PRF which is widely used in periodontal Download this Article
Pages: 21-26
5th Article
Guided Bone Regeneration In Implant Dentistry– A Review The Past Present & Future
Authors: Dr A. Vinu Sarangesh, Dr.V.R. Balaji Mds, Dr.D. Manikandan Mds
Abstract
Post-extraction crestal bone resorption and periodontal disease are
common and unavoidable which can lead to significant ridge dimensional changes. To
regenerate enough bone for successful implant placement, Guided Bone Regeneration has
emerged as a predictable method to enhance the bone volume in deficient recipient sites prior
to implant placement. It provides sufficient bone volume and adequate soft tissue thickness to
enable implants to be placed at the most optimal position from a prosthetic point of view. In
the past, non-absorbable membranes with basic functions such as space maintenance were used
with bone graft materials. Due to several limitations of the non-absorbable membranes,
membranes of the second and third generation equipped with controlled absorbability, and a
functional layer releasing growth factors or antimicrobials were introduced. Moreover, tissue
engineering using biomaterials enabled faster and more stable tissue regeneration. The scaffold
with three-dimensional structures manufactured by computer-aided design and manufacturing
(CAD/CAM) showed high biocompatibility, and promoted cell infiltration and
revascularization Download this Article
Pages:27-31